Description

2-Bromo-6-Fluoro-3-Hydroxy-Benzaldehyde is a versatile and highly functionalized aromatic aldehyde building block. This compound matters for its unique trifunctional reactivity, offering distinct sites for bromination, fluorination, and phenolic hydroxyl groups, which are critical for constructing complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine and bromine substituents can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its halogenated, polar structure.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Bromo-6-Fluoro-3-Hydroxy-Benzaldehyde
CAS No.	1780708-84-0
Molecular Formula	C7H4BrFO2
Molecular Weight	219.01 g/mol
Synonyms	3-Hydroxy-2-bromo-6-fluorobenzaldehyde; 2-Bromo-6-fluoro-3-hydroxybenzenecarboxaldehyde; 6-Fluoro-2-bromo-3-hydroxybenzaldehyde; Benzaldehyde, 2-bromo-6-fluoro-3-hydroxy-; 1780708-84-0; 2-Br-6-F-3-OH-Benzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluoro-3-Hydroxy-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.