Description

1-(2,4-Dichloro-5-Methoxy-Phenyl)-Ethanone is a high-purity, halogenated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Serves as a key precursor in the development of advanced herbicides, fungicides, and insecticides, leveraging its dichloro-methoxy substitution pattern.
• Organic Synthesis Research: Used in academic and industrial laboratories for method development, catalysis studies, and the construction of complex heterocyclic compounds.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers, liquid crystals, or organic electronic materials requiring specific aromatic architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules at various scales.

Basic Information

Product Name	1-(2,4-Dichloro-5-Methoxy-Phenyl)-Ethanone
CAS No.	1780136-12-0
Molecular Formula	C9H8Cl2O2
Molecular Weight	219.07 g/mol
Synonyms	2',4'-Dichloro-5'-Methoxyacetophenone; 5'-Methoxy-2',4'-Dichloroacetophenone; 1-(2,4-Dichloro-5-methoxyphenyl)ethan-1-one; 2,4-Dichloro-5-methoxyacetophenone; Ethanone, 1-(2,4-dichloro-5-methoxyphenyl)-; Acetophenone, 2',4'-dichloro-5'-methoxy-
EINECS	Contact for details

Quality Control

Our 1-(2,4-Dichloro-5-Methoxy-Phenyl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.