Description

(5-Bromo-2-Chlorophenyl)(2-Fluorophenyl)Methanone is a high-purity, halogenated diaryl ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated aromatic motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and CNS-active molecule libraries.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the specific halogen pattern confers desired biological activity and selectivity.
• Material Science Research: Serves as a precursor for synthesizing organic electronic materials, such as ligands for OLEDs or molecular semiconductors.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of bromo and chloro substituents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CMOs for custom synthesis projects requiring precise, multi-halogenated benzophenone cores.

Basic Information

Product Name	(5-Bromo-2-Chlorophenyl)(2-Fluorophenyl)Methanone
CAS No.	1715629-30-3
Molecular Formula	C13H7BrClFO
Molecular Weight	313.55 g/mol
Synonyms	5-Bromo-2-chloro-2'-fluorobenzophenone; 2-Fluoro-5-bromo-2'-chlorobenzophenone; (5-Bromo-2-chlorophenyl)(2-fluorophenyl)methanone; 2'-Fluoro-5-bromo-2-chlorobenzophenone; Methanone, (5-bromo-2-chlorophenyl)(2-fluorophenyl)-; 1-(5-Bromo-2-chlorophenyl)-2-(2-fluorophenyl)ethan-1-one (tautomeric form); Benzophenone, 5-bromo-2-chloro-2'-fluoro-
EINECS	Contact for details

Quality Control

Our (5-Bromo-2-Chlorophenyl)(2-Fluorophenyl)Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.