Description

2,2-Difluoro-1-m-Tolyl-Cyclopropanecarboxylic Acid is a high-value fluorinated cyclopropane derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring a difluorocyclopropane ring fused with a toluic acid moiety, makes it indispensable for introducing conformational rigidity and fluorine atoms into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the research and synthesis of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorinated cyclopropane unit can enhance biological activity and environmental stability.
• Material Science Research: Employed as a monomer or precursor for developing specialty polymers and advanced materials with tailored thermal and chemical resistance properties.
• Ligand and Catalyst Development: Serves as a sophisticated scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research focused on understanding and applying fluorination chemistry and cyclopropane ring strain.

Basic Information

Product Name	2,2-Difluoro-1-m-Tolyl-Cyclopropanecarboxylic Acid
CAS No.	1710345-30-4
Molecular Formula	C11H10F2O2
Molecular Weight	212.19 g/mol
Synonyms	1-(3-Methylphenyl)-2,2-difluorocyclopropane-1-carboxylic Acid; 2,2-Difluoro-1-(3-methylphenyl)cyclopropanecarboxylic Acid; m-Tolyl-2,2-difluorocyclopropanecarboxylic Acid; 3-Methyl-α-(2,2-difluorocyclopropyl)benzoic Acid; DF-m-Tolyl-CCA; CAS 1710345-30-4
EINECS	Contact for details

Quality Control

Every batch of 2,2-Difluoro-1-m-Tolyl-Cyclopropanecarboxylic Acid is manufactured and analyzed under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and process development. A detailed Certificate of Analysis (COA), including purity by HPLC, identity confirmation (IR, NMR), and impurity profile, is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.