Description

4-(Benzyloxy)-3-Chloro-5-Fluorobenzaldehyde is a high-purity, multi-functional aromatic aldehyde building block designed for advanced organic synthesis. This compound matters for its precise molecular architecture, which enables the construction of complex pharmacophores and fine chemicals with high selectivity. It is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the benzyloxy and halogen substituents contribute to biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating complex organic molecules used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The aldehyde and halogen functional groups make it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic & Institutional Research: Utilized in university and government laboratories for methodological studies in synthetic organic chemistry and the development of new catalytic processes.

Basic Information

Product Name	4-(Benzyloxy)-3-Chloro-5-Fluorobenzaldehyde
CAS No.	1709785-15-8
Molecular Formula	C14H10ClFO2
Molecular Weight	264.68 g/mol
Synonyms	3-Chloro-5-fluoro-4-(phenylmethoxy)benzaldehyde; 4-(Benzyloxy)-3-chloro-5-fluorobenzaldehyde; Benzaldehyde, 3-chloro-5-fluoro-4-(phenylmethoxy)-; 3-Chloro-5-fluoro-4-(benzyloxy)benzaldehyde; 4-(Benzyloxy)-3-chloro-5-fluorobenzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-(Benzyloxy)-3-Chloro-5-Fluorobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.