Description

3-(2-Fluoro-Ethoxy)-Cyclobutanecarboxylic Acid is a high-purity fluorinated cyclobutane derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring a carboxylic acid group and a fluoroethoxy side chain, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in drug discovery and advanced material science.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Research: Used in the synthesis of advanced herbicides and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Building block for synthesizing fluorinated polymers and specialty chemicals with unique surface properties and resistance.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological mechanisms and diagnostics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and scale-up development.

Basic Information

Product Name	3-(2-Fluoro-Ethoxy)-Cyclobutanecarboxylic Acid
CAS No.	1708160-35-3
Molecular Formula	C7H11FO3
Molecular Weight	162.16 g/mol
Synonyms	3-(2-Fluoroethoxy)cyclobutanecarboxylic acid; 3-(2-Fluoroethoxy)cyclobutane-1-carboxylic acid; Cyclobutanecarboxylic acid, 3-(2-fluoroethoxy)-; 1708160-35-3; 3-(2-Fluoroethoxy)cyclobutanecarboxylate; 3-(2-Fluoroethoxy)-1-cyclobutanecarboxylic acid; 1-Carboxy-3-(2-fluoroethoxy)cyclobutane
EINECS	Contact for details

Quality Control

Our 3-(2-Fluoro-Ethoxy)-Cyclobutanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.