Description

(E)-Ethyl 3-(4-(1-(2-Aminoethyl)-Pyrrolidin-2-Yl)Phenyl)Acrylate is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture. This compound is critical for the synthesis of sophisticated active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex APIs, especially for central nervous system (CNS) and receptor-targeted therapies.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Preclinical Studies: Serves as a precursor for generating compounds used in pharmacological and toxicological evaluations.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals for clients.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and enzyme functions.

Basic Information

Item	Detail
Product Name	(E)-Ethyl 3-(4-(1-(2-Aminoethyl)-Pyrrolidin-2-Yl)Phenyl)Acrylate
CAS No.	1706519-96-1
Molecular Formula	C18H26N2O2
Molecular Weight	302.41 g/mol
Synonyms	Ethyl (E)-3-[4-[1-(2-Aminoethyl)pyrrolidin-2-yl]phenyl]acrylate; (E)-Ethyl 3-(4-(1-(2-Aminoethyl)-2-pyrrolidinyl)phenyl)-2-propenoate; 1706519-96-1; UNII-9K7F4S8R4I; 2-Propenoic acid, 3-[4-[1-(2-aminoethyl)-2-pyrrolidinyl]phenyl]-, ethyl ester, (E)-; Ethyl (E)-3-(4-(1-(2-aminoethyl)pyrrolidin-2-yl)phenyl)acrylate; AKOS040759195; AS-76379
EINECS	Contact for details

Quality Control

Our (E)-Ethyl 3-(4-(1-(2-Aminoethyl)-Pyrrolidin-2-Yl)Phenyl)Acrylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.