Description

2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Benzenesulfonylchloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its value lies in its unique molecular architecture, combining a reactive sulfonyl chloride group with fluorine and methoxy substituents, making it a critical intermediate for creating complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl and fluorine groups enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and advanced materials with specific surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Benzenesulfonylchloride
CAS No.	1706435-15-5
Molecular Formula	C8H5ClF4O3S
Molecular Weight	292.64 g/mol
Synonyms	2-Fluoro-5-methoxy-3-(trifluoromethyl)benzenesulfonyl chloride; 3-(Trifluoromethyl)-2-fluoro-5-methoxybenzenesulfonyl chloride; 2-Fluoro-5-methoxy-alpha,alpha,α-trifluoro-m-toluenesulfonyl chloride; 1-Fluoro-4-methoxy-2-[(trifluoromethyl)sulfonyl]benzene (tautomeric form); 1706435-15-5; CAS 1706435-15-5
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Benzenesulfonylchloride adheres to a stringent quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports compliance in cGMP (current Good Manufacturing Practice) environments for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.