Description

3,4-Dichloro-5-(Trifluoromethoxy)Benzyl Bromide is a high-purity, multi-functional benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of halogen substituents and the trifluoromethoxy group, which are essential for modulating the biological activity, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used to construct advanced herbicide and fungicide molecules, where the dichloro and trifluoromethoxy groups contribute to enhanced efficacy and environmental persistence.
• Ligand & Catalyst Development: Serves as a versatile alkylating agent for the preparation of specialized phosphine ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of novel monomers or functionalized polymers with specific electronic or surface properties.
• Chemical Biology Probes: Useful for the site-specific modification of biomolecules or the synthesis of activity-based probes for target identification.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3,4-Dichloro-5-(Trifluoromethoxy)Benzyl Bromide
CAS No.	1706435-11-1
Molecular Formula	C9H4BrCl2F3O
Molecular Weight	344.39 g/mol
Synonyms	1-(Bromomethyl)-3,4-dichloro-5-(trifluoromethoxy)benzene; (3,4-Dichloro-5-(trifluoromethoxy)phenyl)methyl bromide; 3,4-Dichloro-α-(bromomethyl)-α-(trifluoromethoxy)toluene; Benzyl bromide, 3,4-dichloro-5-(trifluoromethoxy)-; 5-(Bromomethyl)-1,2-dichloro-3-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-5-(Trifluoromethoxy)Benzyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.