Description

Potassium (3-((2-Bromophenyl)Amino)-3-Oxopropyl)Trifluoroborate is a specialized organotrifluoroborate salt, a valuable class of reagents in modern synthetic chemistry. This compound is prized for its enhanced stability and handling characteristics compared to traditional boronic acids, making it a crucial building block for cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the efficient synthesis of complex molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a stable, air- and moisture-tolerant boron reagent for the formation of carbon-carbon bonds, essential in constructing biaryl and heterobiaryl structures prevalent in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Serves as a key precursor in the multi-step synthesis of drug candidates, particularly those containing brominated aromatic systems.
• Agrochemical Research & Development: Used in the creation of novel herbicides, fungicides, and insecticides where specific bromo-aniline derivatives are required.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors and light-emitting materials for electronic displays.
• Library Synthesis for Drug Discovery: Facilitates high-throughput parallel synthesis to generate diverse compound libraries for biological screening.
• Process Chemistry & Scale-Up: Its improved stability profile makes it suitable for optimizing and scaling synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	Potassium (3-((2-Bromophenyl)Amino)-3-Oxopropyl)Trifluoroborate
CAS No.	1705578-22-8
Molecular Formula	C9H9BBrF3KNO
Molecular Weight	330.09 g/mol
Synonyms	Potassium 2-Bromo-N-(3,3,3-trifluoro-2-hydroxy-1-oxopropyl)anilinyltrifluoroborate; Potassium (3-((2-Bromophenyl)amino)-3-oxopropyl)trifluoroboranuide; 2-Bromophenylamido Potassium Trifluoroborate Propionyl Derivative; Potassium 3-((2-Bromophenyl)amino)-1,1,1-trifluoro-3-oxopropan-1-yltrifluoroborate; (2-Bromoanilino)carbonylethyltrifluoroborate Potassium Salt; K-ATE Complex of 3-((2-Bromophenyl)amino)-3-oxopropylboronic acid
EINECS	Contact for details

Quality Control

Every batch of Potassium (3-((2-Bromophenyl)Amino)-3-Oxopropyl)Trifluoroborate is manufactured under strict quality management systems. We employ advanced analytical techniques including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC, and KF titration to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment. Recommended long-term storage at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) is advised to maintain optimal stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0 %
NMR Purity (¹H)	≥ 95%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.