Description

Potassium (3-Chloro-2-Morpholinopyridin-4-Yl)Trifluoroborate is a high-value organotrifluoroborate salt, a crucial class of reagents in modern synthetic chemistry. Its primary value lies in its exceptional stability and utility as a coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl scaffolds. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a key building block for active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those containing complex pyridine and morpholine motifs.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a stable, air- and moisture-tolerant organoboron reagent for palladium-catalyzed carbon-carbon bond formation.
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science Research: Serves as a precursor for creating organic electronic materials and functionalized ligands for catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and target engagement.
• Process Chemistry: Valued for its robustness in scaling up synthetic routes from laboratory to pilot plant and manufacturing scales.

Basic Information

Product Name	Potassium (3-Chloro-2-Morpholinopyridin-4-Yl)Trifluoroborate
CAS No.	1704704-32-4
Molecular Formula	C9H11BClF3KN2O
Molecular Weight	314.55 g/mol
Synonyms	Potassium (3-Chloro-2-morpholin-4-ylpyridin-4-yl)trifluoroborate; 3-Chloro-2-morpholinopyridine-4-trifluoroboronic acid potassium salt; 4-(3-Chloro-2-morpholin-4-yl-4-pyridyl)trifluoroborate potassium; Potassium 3-Chloro-2-morpholinopyridine-4-trifluoroboronate; (3-Chloro-2-morpholinopyridin-4-yl)trifluoroboronic acid potassium salt; 3-Chloro-2-(morpholin-4-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine potassium trifluoroborate derivative
EINECS	Contact for details

Quality Control

Our Potassium (3-Chloro-2-Morpholinopyridin-4-Yl)Trifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay (by NMR/HPLC), identity confirmation, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain long-term stability. Keep the container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
Assay (NMR)	≥90%
Water Content (KF)	≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.