Description

1-(5-Bromo-4-Chloro-2-Fluoro-Phenyl)-Ethanone is a high-purity, multi-halogenated aromatic ketone building block of significant importance in advanced organic synthesis. Its precise halogen substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogenated phenyl ring contributes to biological activity and stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating molecular probes, tags, and linkers in biochemical research and drug discovery platforms.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(5-Bromo-4-Chloro-2-Fluoro-Phenyl)-Ethanone
CAS No.	1704367-12-3
Molecular Formula	C8H5BrClFO
Molecular Weight	251.48 g/mol
Synonyms	5-Bromo-4-chloro-2-fluoroacetophenone; 1-Acetyl-5-bromo-4-chloro-2-fluorobenzene; 2-Fluoro-5-bromo-4-chloroacetophenone; 2'-Fluoro-5'-bromo-4'-chloroacetophenone; Ethanone, 1-(5-bromo-4-chloro-2-fluorophenyl)-; (5-Bromo-4-chloro-2-fluorophenyl)ethanone; 5-Bromo-4-chloro-2-fluorophenyl methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-4-Chloro-2-Fluoro-Phenyl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.