Description

(4-((4-Methylpiperidin-1-yl)sulfonyl)naphthalen-1-yl)boronic acid is a high-purity, functionalized boronic acid derivative designed for advanced synthetic chemistry. This compound is a critical building block in modern pharmaceutical research and development, particularly for the construction of complex molecules via Suzuki-Miyaura cross-coupling reactions. It is essential for medicinal chemists and process development scientists working in drug discovery, agrochemical research, and materials science who require reliable, high-quality intermediates for creating novel sulfonamide-containing scaffolds.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing naphthalene and piperidine motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid partner for palladium-catalyzed carbon-carbon bond formation to create biaryl and heterobiaryl structures.
• Medicinal Chemistry & Drug Discovery: Used in library synthesis for structure-activity relationship (SAR) studies and lead optimization programs targeting various disease pathways.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science & OLED Development: Acts as a precursor for creating organic electronic materials, such as charge-transport layers or emissive materials in OLED devices.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and inhibitors to study enzyme function and biological pathways.

Basic Information

Product Name	(4-((4-Methylpiperidin-1-yl)sulfonyl)naphthalen-1-yl)boronic Acid
CAS No.	1704121-04-9
Molecular Formula	C₁₆H₂₀BNO₄S
Molecular Weight	333.21 g/mol
Synonyms	1-(4-Methylpiperidine-1-sulfonyl)-4-boronic acid naphthalene; 4-(4-Methyl-1-piperidylsulfonyl)-1-naphthaleneboronic acid; 4-(N-4-Methylpiperidylsulfonyl)-1-naphthaleneboronic acid; 4-(4-Methylpiperidine-1-sulfonyl)naphthalene-1-boronic acid; B-[4-[(4-Methyl-1-piperidinyl)sulfonyl]-1-naphthalenyl]boronic acid; (4-(4-Methylpiperidine-1-sulfonyl)naphthalen-1-yl)boronic acid
EINECS	Contact for details

Quality Control

Our (4-((4-Methylpiperidin-1-yl)sulfonyl)naphthalen-1-yl)boronic acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.