Description

2-(4-Methylpiperidin-1-Yl)-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide is a high-value pharmaceutical intermediate and building block featuring a boronic ester pinacol group, which is essential for modern cross-coupling reactions like the Suzuki-Miyaura reaction. This compound matters because it enables the efficient and precise construction of complex molecules, accelerating research and development in medicinal chemistry. It is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Utilized in palladium-catalyzed reactions to form carbon-carbon bonds, a cornerstone of modern synthetic organic chemistry.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides with targeted modes of action.
• Material Science: Used in the creation of organic electronic materials, such as those for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of activity-based probes for target identification.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	2-(4-Methylpiperidin-1-Yl)-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide
CAS No.	1704120-84-2
Molecular Formula	C20H31BN2O3
Molecular Weight	358.29 g/mol
Synonyms	2-(4-Methyl-1-piperidinyl)-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]aniline; 1704120-84-2; BRN 23795856; AKOS040759948; ZINC000257830911; (4-(2-(4-Methylpiperidine-1-carboxamido)acetyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(4-Methylpiperidin-1-Yl)-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	95.0% - 105.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.