Description

(2-Methoxy-5-(Piperazin-1-Ylsulfonyl)Phenyl)Boronic Acid Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block for organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and other targeted therapeutic areas. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: The boronic acid functional group makes it an essential reagent for forming carbon-carbon bonds, a fundamental step in constructing complex organic frameworks.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• Chemical Biology Research: Employed as a probe or precursor in the development of chemical tools for studying biological pathways.
• Process Chemistry Development: Serves as a starting material for scaling up the production of target molecules from laboratory to pilot and commercial scale.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific compounds.

Basic Information

Product Name	(2-Methoxy-5-(Piperazin-1-Ylsulfonyl)Phenyl)Boronic Acid Hydrochloride
CAS No.	1704095-65-7
Molecular Formula	C11H18BN2O5S • HCl
Molecular Weight	~348.61 g/mol (Free base)
Synonyms	2-Methoxy-5-(piperazine-1-sulfonyl)phenylboronic acid hydrochloride; 5-(Piperazin-1-ylsulfonyl)-2-methoxyphenylboronic acid HCl; [2-Methoxy-5-(1-piperazinylsulfonyl)phenyl]boronic acid hydrochloride; B-[2-Methoxy-5-(piperazin-1-ylsulfonyl)phenyl]boronic acid hydrochloride; (2-Methoxy-5-piperazin-1-ylsulfonyl-phenyl)boronic acid hydrochloride; CAS 1704095-65-7; Sulfonylpiperazine phenylboronic acid derivative HCl salt
EINECS	Contact for details

Quality Control

Our (2-Methoxy-5-(Piperazin-1-Ylsulfonyl)Phenyl)Boronic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and cGMP starting materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.