Description

4-Methyl-1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Piperidine is a high-value, synthetically versatile boronic ester derivative, serving as a critical building block in modern organic synthesis. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures in pharmaceutical and advanced material research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-purity intermediates for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require the introduction of complex aryl-piperidine motifs.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers, organic light-emitting diodes (OLEDs), and conductive polymers.
• Ligand and Catalyst Development: Serves as a starting material for creating novel bidentate ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A vital intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	4-Methyl-1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Piperidine
CAS No.	1704095-28-2
Molecular Formula	C18H28BNO2
Molecular Weight	301.24 g/mol
Synonyms	4-Methyl-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine; 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-4-methylpiperidine; 4-Methyl-1-(4-(pinacolatoboron)phenyl)piperidine; 4-Methyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine; 1704095-28-2; 4-Methyl-1-(4-(pinacolboron)phenyl)piperidine; 1-(4-(Pinacolatoboron)phenyl)-4-methylpiperidine
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Piperidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.