Description

(3-(1,4-Dioxa-8-Azaspiro[4.5]Decan-8-Ylsulfonyl)Phenyl)Boronic Acid is a sophisticated organoboron building block featuring a spirocyclic sulfonamide protecting group. This compound is critical for enabling complex cross-coupling reactions, particularly in the synthesis of pharmaceutical intermediates and advanced materials. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, structurally complex boronic acids for Suzuki-Miyaura coupling.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require complex aromatic structures.
• Material Science & OLED Development: Serves as a building block for creating organic electronic materials, including charge-transport layers and emissive materials in OLED displays.
• Ligand & Catalyst Design: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Development: Useful for synthesizing boronic acid-based probes for sensing, imaging, and protein labeling applications.
• Polymer Chemistry: Can be incorporated into polymer backbones or as functional end-groups to create advanced polymeric materials with specific properties.

Basic Information

Product Name	(3-(1,4-Dioxa-8-Azaspiro[4.5]Decan-8-Ylsulfonyl)Phenyl)Boronic Acid
CAS No.	1704073-79-9
Molecular Formula	C17H24BNO6S
Molecular Weight	381.15 g/mol
Synonyms	3-(1,4-Dioxa-8-azaspiro[4.5]decane-8-sulfonyl)benzeneboronic acid; 3-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenylboronic acid; 8-[3-(Boronophenyl)sulfonyl]-1,4-dioxa-8-azaspiro[4.5]decane; (3-((1,4-Dioxa-8-azaspiro[4.5]decan-8-yl)sulfonyl)phenyl)boronic acid; B-[3-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our (3-(1,4-Dioxa-8-Azaspiro[4.5]Decan-8-Ylsulfonyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.