Description

(4-(1-(4-Methylpiperazin-1-Yl)Ethyl)Phenyl)Boronic Acid Hydrochloride is a high-purity, advanced pharmaceutical intermediate and versatile organoboron building block. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a critical step in constructing complex molecules for drug discovery and development. This compound is essential for medicinal chemistry researchers and process development scientists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical organoboron reagent for forming carbon-carbon bonds to create biaryl structures, a common motif in modern pharmaceuticals.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and lead optimization libraries to explore new chemical entities and structure-activity relationships (SAR).
• Process Chemistry & API Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Agrochemical Research: Utilized as a precursor in the development of new herbicides, fungicides, and insecticides with complex molecular architectures.
• Material Science: Potential use in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) where specific boronic acid functionalities are required.

Basic Information

Product Name	(4-(1-(4-Methylpiperazin-1-Yl)Ethyl)Phenyl)Boronic Acid Hydrochloride
CAS No.	1704069-16-8
Molecular Formula	C13H22BClN2O2
Molecular Weight	284.59 g/mol
Synonyms	[4-[1-(4-Methyl-1-piperazinyl)ethyl]phenyl]boronic acid hydrochloride; 4-(1-(4-Methylpiperazin-1-yl)ethyl)benzeneboronic acid hydrochloride; (4-(1-(4-Methylpiperazin-1-yl)ethyl)phenyl)boronic acid HCl; Boronic acid, B-[4-[1-(4-methyl-1-piperazinyl)ethyl]phenyl]-, hydrochloride; 1704069-16-8; 4-(1-(4-Methylpiperazin-1-yl)ethyl)phenylboronic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (4-(1-(4-Methylpiperazin-1-Yl)Ethyl)Phenyl)Boronic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.