Description

4-Methyl-3-(Morpholinosulfonyl)Phenylboronic Acid is a specialized organoboron compound featuring a morpholinosulfonyl substituent, making it a valuable building block in modern synthetic chemistry. Its primary value lies in its role as a key intermediate in cross-coupling reactions, such as the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecular architectures. This high-purity boronic acid is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with improved efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and organic electronic materials.
• Chemical Research: A versatile reagent in academic and industrial R&D for constructing complex biaryl and heterobiaryl structures via palladium-catalyzed cross-coupling.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands and organometallic catalysts for asymmetric synthesis.
• Diagnostic Reagent Manufacturing: Used in the production of probes and sensors for biochemical assays and diagnostic applications.

Basic Information

Product Name	4-Methyl-3-(Morpholinosulfonyl)Phenylboronic Acid
CAS No.	1704065-60-0
Molecular Formula	C11H16BNO4S
Molecular Weight	269.13 g/mol
Synonyms	3-(Morpholine-4-sulfonyl)-4-methylbenzeneboronic acid; [3-(Morpholin-4-ylsulfonyl)-4-methylphenyl]boronic acid; 4-Methyl-3-(4-morpholinesulfonyl)benzeneboronic acid; 4-Methyl-3-morpholinosulfonylphenylboronic acid; B-[3-(Morpholine-4-sulfonyl)-4-methylphenyl]boronic acid; 1704065-60-0; 4-Methyl-3-(morpholinosulfonyl)phenylboronic acid pinacol ester (common precursor).
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-(Morpholinosulfonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.