Description

4-Fluoro-3-(Morpholinomethyl)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group with a morpholine moiety, making it an essential reagent for constructing complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a fluorinated phenyl and morpholine pharmacophore.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, enabling the construction of biaryl and heterobiaryl structures central to many bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where its specific substitution pattern can enhance biological activity.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and advanced polymers.
• Chemical Biology & Proteomics: Can be utilized in the development of chemical probes and affinity ligands for studying biological systems.

Basic Information

Product Name	4-Fluoro-3-(Morpholinomethyl)Phenylboronic Acid
CAS No.	1704063-95-5
Molecular Formula	C11H15BFNO3
Molecular Weight	239.06 g/mol
Synonyms	[4-Fluoro-3-(morpholin-4-ylmethyl)phenyl]boronic acid; 3-(Morpholinomethyl)-4-fluorobenzeneboronic acid; 4-Fluoro-3-morpholin-4-ylmethylbenzeneboronic acid; B-[4-Fluoro-3-(morpholinomethyl)phenyl]boronic acid; 1704063-95-5; 4-Fluoro-3-morpholinomethylphenylboronic Acid Pinacol Ester (common precursor); AKOS006361950 (catalog ID); FT-0773293 (catalog ID)
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Morpholinomethyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical: 97-99%)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.