Description

(3-(2-(4-Hydroxypiperidin-1-Yl)Ethoxy)Phenyl)Boronic Acid is a sophisticated boronic acid derivative featuring a hydroxypiperidine-ethoxy linker, designed for advanced synthetic applications. This compound matters as a key building block in modern medicinal chemistry, enabling the formation of stable carbon-boron bonds critical for Suzuki-Miyaura cross-coupling reactions. Pharmaceutical researchers and fine chemical manufacturers need it for the efficient synthesis of complex molecules, particularly in developing targeted therapeutics and novel chemical entities. Its specific structure offers a valuable handle for constructing diverse compound libraries and bioactive intermediates.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS research.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to create complex biaryl structures, a cornerstone of modern organic synthesis.
• Proteolysis-Targeting Chimera (PROTAC) Development: Serves as a linker component in the design of bifunctional molecules for targeted protein degradation.
• Chemical Biology & Probe Synthesis: Used to create molecular probes for studying enzyme function, protein interactions, and cellular pathways.
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers with tailored properties.
• Agrochemical Intermediate: A precursor in the development of novel, high-performance crop protection agents with specific modes of action.

Basic Information

Product Name	(3-(2-(4-Hydroxypiperidin-1-Yl)Ethoxy)Phenyl)Boronic Acid
CAS No.	1704063-52-4
Molecular Formula	C13H20BNO4
Molecular Weight	265.12 g/mol
Synonyms	[3-[2-(4-Hydroxypiperidin-1-yl)ethoxy]phenyl]boronic acid; 1-(2-{3-[(Hydroxy)boranyl]phenoxy}ethyl)-4-piperidinol; 3-[2-(4-Hydroxy-1-piperidinyl)ethoxy]benzeneboronic acid; Boronic acid, B-[3-[2-(4-hydroxy-1-piperidinyl)ethoxy]phenyl]-; (3-(2-(4-Hydroxy-piperidin-1-yl)-ethoxy)-phenyl)-boronic acid; CAS 1704063-52-4; Hydroxypiperidine Phenylboronic Acid Derivative
EINECS	Contact for details

Quality Control

Our (3-(2-(4-Hydroxypiperidin-1-Yl)Ethoxy)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure compliance with stringent industry standards. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our commitment to quality assurance and supply reliability supports your critical research and development timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to maintain stability and purity. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.