Description

4-(3-(4-Ethylpiperazin-1-Yl)Propoxy)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a piperazine moiety that offers opportunities for further derivatization and solubility modulation. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who are developing novel active ingredients, particularly for targeted therapies and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted small-molecule drugs.
• Agrochemical Research: Used in constructing novel herbicide and fungicide candidates through palladium-catalyzed cross-coupling reactions.
• Material Science: Serves as a monomer or linker in the development of advanced organic polymers and functional materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Ligand Synthesis: The piperazine moiety can be utilized to create novel ligands for catalysis or metal-organic frameworks (MOFs).
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening and drug discovery programs.

Basic Information

Product Name	4-(3-(4-Ethylpiperazin-1-Yl)Propoxy)Phenylboronic Acid
CAS No.	1704063-50-2
Molecular Formula	C₁₅H₂₅BN₂O₃
Molecular Weight	292.19 g/mol
Synonyms	4-[3-(4-Ethyl-1-piperazinyl)propoxy]benzeneboronic Acid; [4-[3-(4-Ethylpiperazin-1-yl)propoxy]phenyl]boronic Acid; 4-(3-(4-Ethylpiperazin-1-yl)propoxy)benzeneboronic Acid; B-[4-[3-(4-Ethyl-1-piperazinyl)propoxy]phenyl]-B-boronic Acid; 1704063-50-2; 4-(3-(4-Ethylpiperazin-1-yl)propoxy)phenylboronic acid pinacol ester (precursor); EPPBA (abbreviation)
EINECS	Contact for details

Quality Control

Our 4-(3-(4-Ethylpiperazin-1-Yl)Propoxy)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.