Description

2,3-Dimethoxy-5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is a high-value, multi-functional boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and functional organic materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a precursor for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Employed in the development of molecular probes and sensors for diagnostic and research applications.
• Academic & Industrial R&D: A versatile reagent for methodology development and library synthesis in medicinal and process chemistry.
• Custom Synthesis: A starting point for the contract manufacturing of specialty fine chemicals and bespoke boronic acid derivatives.

Basic Information

Item	Details
Product Name	2,3-Dimethoxy-5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile
CAS No.	1701449-79-7
Molecular Formula	C15H20BNO4
Molecular Weight	289.14 g/mol
Synonyms	5-Cyano-2,3-dimethoxyphenylboronic acid pinacol ester; 2,3-Dimethoxy-5-cyanophenylboronic acid pinacol ester; (5-Cyano-2,3-dimethoxyphenyl)boronic acid pinacol ester; 2-(5-Cyano-2,3-dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1701449-79-7; PINACOL 2,3-DIMETHOXY-5-CYANOPHENYLBORONATE
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dimethoxy-5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard quality commitment includes comprehensive analysis via HPLC, NMR (¹H and ¹³C), and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.