Description

3-Chloro-4-Ethoxy-5-Methoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs) and novel organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific biaryl motifs.
• Material Science Research: Serves as a monomer or building block for creating organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the development of chemical probes and inhibitors that target specific enzymes or biological pathways.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic synthesis and catalysis research.
• Fine Chemical Production: Integral to the custom synthesis of specialty chemicals and complex organic molecules for various industrial applications.

Basic Information

Product Name	3-Chloro-4-Ethoxy-5-Methoxyphenylboronic Acid
CAS No.	1701449-09-3
Molecular Formula	C9H12BClO4
Molecular Weight	230.45 g/mol
Synonyms	(3-Chloro-4-ethoxy-5-methoxyphenyl)boronic acid; 3-Chloro-4-ethoxy-5-methoxybenzeneboronic acid; Boronic acid, B-(3-chloro-4-ethoxy-5-methoxyphenyl)-; 1701449-09-3; AKOS026713186; 3-CHLORO-4-ETHOXY-5-METHOXYPHENYLBORONIC ACID; (3-Chloro-4-ethoxy-5-methoxyphenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Ethoxy-5-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.