Description

2-Chloro-5-Iodo-4-Methyl-Benzoic Acid Methyl Ester is a high-purity, multi-functional halogenated aromatic ester serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting specific receptor sites where halogen atoms are crucial for binding.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other advanced functional materials due to its aromatic core and halogen substituents.
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological processes, where the iodine atom can be used for further functionalization or labeling.
• Custom Synthesis and Scale-Up: An important substrate for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	2-Chloro-5-Iodo-4-Methyl-Benzoic Acid Methyl Ester
CAS No.	1699509-67-5
Molecular Formula	C9H8ClIO2
Molecular Weight	310.52 g/mol
Synonyms	Methyl 2-Chloro-5-iodo-4-methylbenzoate; Benzoic acid, 2-chloro-5-iodo-4-methyl-, methyl ester; 4-Methyl-2-chloro-5-iodobenzoic acid methyl ester; 2-Chloro-5-iodo-p-toluic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Iodo-4-Methyl-Benzoic Acid Methyl Ester is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.