Description

1-(5-Amino-4-Bromo-2-Chloro-Phenyl)-Ethanone is a high-purity halogenated aromatic ketone building block of significant importance in advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty dyes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of complex, high-performance organic dyes and pigments.
• Chemical Biology Probes: Utilized in research to develop molecular probes and tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	1-(5-Amino-4-Bromo-2-Chloro-Phenyl)-Ethanone
CAS No.	1698027-12-1
Molecular Formula	C8H7BrClNO
Molecular Weight	248.51 g/mol
Synonyms	5-Amino-4-bromo-2-chloroacetophenone; 1-(5-Amino-4-bromo-2-chlorophenyl)ethan-1-one; 4-Bromo-5-amino-2-chloroacetophenone; 2-Chloro-5-amino-4-bromoacetophenone; Acetophenone, 5-amino-4-bromo-2-chloro-; Ethanone, 1-(5-amino-4-bromo-2-chlorophenyl)-
EINECS	Contact for details

Quality Control

Our 1-(5-Amino-4-Bromo-2-Chloro-Phenyl)-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.