Description

Methyl 3-(4-Iodophenyl)-3-Oxopropionate is a high-value iodinated aromatic ketoester building block, essential for advanced organic synthesis. Its core value lies in providing a versatile molecular scaffold for constructing complex heterocycles and pharmaceutical intermediates. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry and fine chemical production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and photoactive materials due to its conjugated aromatic structure.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form complex biaryl structures.
• Heterocyclic Chemistry: Fundamental starting material for the synthesis of various heterocycles like pyrazoles, isoxazoles, and pyridines.
• Chemical Biology Probes: Utilized in creating labeled compounds and molecular probes for biochemical and diagnostic research.

Basic Information

Product Name	Methyl 3-(4-Iodophenyl)-3-Oxopropionate
CAS No.	1691841-09-4
Molecular Formula	C10H9IO3
Molecular Weight	304.08 g/mol
Synonyms	Methyl 4-Iodobenzoylacetate; 3-(4-Iodophenyl)-3-oxopropanoic Acid Methyl Ester; Methyl (4-Iodobenzoyl)acetate; Methyl 3-Oxo-3-(4-iodophenyl)propanoate; 4-Iodobenzoylacetic Acid Methyl Ester; Methyl β-(4-Iodobenzoyl)propionate; Acetic acid, (4-iodobenzoyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(4-Iodophenyl)-3-Oxopropionate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.