Description

2,4-Dichloro-3-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl or heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the dichloro-methoxyphenyl moiety is a common pharmacophore.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and enzyme inhibitors for target identification and validation studies.
• Ligand & Catalyst Development: Utilized as a starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,4-Dichloro-3-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	1689538-76-8
Molecular Formula	C13H17BCl2O3
Molecular Weight	303.00 g/mol
Synonyms	2,4-Dichloro-3-methoxyphenylboronic acid pinacol ester; (2,4-Dichloro-3-methoxyphenyl)boronic acid pinacol ester; 2-(2,4-Dichloro-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-(2,4-dichloro-3-methoxyphenyl)-1,3,2-dioxaborolane; Pinacol (2,4-dichloro-3-methoxyphenyl)boronate; Boronic acid, B-(2,4-dichloro-3-methoxyphenyl)-, 1,1-dimethylethyl ester; 2,4-Dichloro-3-methoxybenzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-3-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.