Description

2-Chloro-6-Isopropylpyridine-3-Boronic Acid Pinacol Ester is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl and heterobiaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules. Its specific substitution pattern offers unique regioselectivity in coupling reactions.

Application

• Pharmaceutical Intermediate: Critical for synthesizing novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and charge-transport materials.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and tool compounds for target identification and validation.
• Catalyst Ligand Development: Acts as a starting material for constructing sophisticated ligand frameworks in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-6-Isopropylpyridine-3-Boronic Acid Pinacol Ester
CAS No.	1689528-51-5
Molecular Formula	C14H19BClNO2
Molecular Weight	279.57 g/mol
Synonyms	2-Chloro-6-(propan-2-yl)pyridine-3-boronic acid pinacol ester; (2-Chloro-6-isopropylpyridin-3-yl)boronic acid pinacol ester; 2-Chloro-6-isopropyl-3-pyridineboronic acid pinacol ester; Pinacol 2-chloro-6-isopropylpyridine-3-boronate; 2-Chloro-6-(1-methylethyl)-3-pyridineboronic acid, pinacol ester; B-(2-Chloro-6-isopropyl-3-pyridinyl)boronic acid pinacol ester; 1689528-51-5; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Isopropylpyridine-3-Boronic Acid Pinacol Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with relevant regulatory frameworks for our customers' target markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.