Description

5-Chloro-2-Ethoxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its boronate ester functionality.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for studying biological pathways and protein interactions.
• Custom Fine Chemical Production: An important reagent for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds.

Basic Information

Item	Detail
Product Name	5-Chloro-2-Ethoxyphenylboronic Acid Pinacol Ester
CAS No.	1689512-53-5
Molecular Formula	C14H20BClO3
Molecular Weight	282.57 g/mol
Synonyms	5-Chloro-2-ethoxyphenylboronic acid pinacol ester; (5-Chloro-2-ethoxyphenyl)boronic acid pinacol ester; 2-(5-Chloro-2-ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Chloro-2-ethoxybenzeneboronic acid pinacol ester; Pinacol (5-chloro-2-ethoxyphenyl)boronate; CAS 1689512-53-5
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Ethoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full batch traceability are provided to guarantee consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.