Description

4-Propoxy-2-Methylphenylboronic Acid, Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a critical protected boronic acid building block, enabling efficient cross-coupling reactions in complex molecule assembly. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for Suzuki-Miyaura coupling and other palladium-catalyzed transformations.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific biphenyl or heterobiaryl scaffolds.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and organic semiconductors, where precise molecular architecture is crucial.
• Chemical Biology & Probe Development: Utilized as a precursor for bioconjugation reagents or fluorescent probes targeting biological systems.
• Academic & Process R&D: A versatile reagent for method development and scaling up novel synthetic routes in organic chemistry.
• Ligand & Catalyst Preparation: Serves as a precursor for sophisticated ligand systems used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	4-Propoxy-2-Methylphenylboronic Acid, Pinacol Ester
CAS No.	1688702-80-8
Molecular Formula	C₁₇H₂₇BO₃
Molecular Weight	290.21 g/mol
Synonyms	2-Methyl-4-propoxyphenylboronic acid pinacol ester; 4-Propoxy-2-methylbenzeneboronic acid pinacol ester; (4-Propoxy-2-methylphenyl)boronic acid pinacol ester; 2-Methyl-4-propoxybenzeneboronic acid pinacol ester; Pinacol (4-propoxy-2-methylphenyl)boronate; B-(4-Propoxy-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1688702-80-8; 4-Propoxy-2-methylphenylboronic acid neopentyl glycol ester (common alternative)
EINECS	Contact for details

Quality Control

Our 4-Propoxy-2-Methylphenylboronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (NMR)	≥95.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.