Description

2-Bromo-6-(Trifluoromethyl)Pyridine-3-Boronic Acid CAS NO 1688675-75-3 is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures through versatile cross-coupling reactions. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in drug discovery for oncology and CNS targets.
• Agrochemical Synthesis: Used to construct complex pyridine-based scaffolds for developing new generation herbicides, fungicides, and insecticides with improved efficacy.
• Ligand & Catalyst Development: Serves as a building block for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and polymerization processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs and other optoelectronic devices.
• Chemical Biology & Probe Design: Utilized to create molecular probes and labeled compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Bromo-6-(Trifluoromethyl)Pyridine-3-Boronic Acid
CAS No.	1688675-75-3
Molecular Formula	C6H4BBrF3NO2
Molecular Weight	269.82 g/mol
Synonyms	2-Bromo-6-(trifluoromethyl)pyridine-3-boronic acid; [2-Bromo-6-(trifluoromethyl)-3-pyridinyl]boronic acid; 3-Borono-2-bromo-6-(trifluoromethyl)pyridine; 2-Bromo-6-trifluoromethylpyridine-3-boronic acid; 2-Bromo-6-(trifluoromethyl)-3-pyridineboronic acid; Boronic acid, B-[2-bromo-6-(trifluoromethyl)-3-pyridinyl]-; 1688675-75-3
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(Trifluoromethyl)Pyridine-3-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon/nitrogen) for long-term stability and to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.