Description

2-[2-(Methoxymethyl)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound matters because it provides a stable and reactive handle for Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex organic molecules. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in constructing complex molecules for new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules in proteomics and diagnostic assay development.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new chemical spaces in synthetic organic chemistry laboratories.

Basic Information

Product Name	2-[2-(Methoxymethyl)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1688661-75-7
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	2-(2-(Methoxymethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-(Methoxymethyl)phenyl)boronic acid pinacol ester; 2-(Methoxymethyl)phenylboronic acid pinacol ester; [2-(Methoxymethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol [2-(methoxymethyl)phenyl]boronate; B-[2-(Methoxymethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-[2-(Methoxymethyl)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and lot-to-lot consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.