Description

3-Chloro-4-Propoxyphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily used by R&D chemists and process development scientists in the life sciences sector to construct complex biaryl and heterobiaryl scaffolds, accelerating the discovery of new active ingredients.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing substituted biphenyl or phenyl-heteroaryl motifs.
• Agrochemical Research: Used to create novel herbicide and fungicide candidates by introducing the chloropropoxyphenyl moiety into target molecules.
• Material Science: Serves as a precursor for constructing organic electronic materials, such as ligands for OLEDs or molecular wires.
• Chemical Biology: Employed in the development of molecular probes and enzyme inhibitors where the boronic ester group acts as a versatile handle for further functionalization.
• Academic & Contract Research: A staple building block in university and CRO laboratories for methodological development and library synthesis in medicinal chemistry programs.

Basic Information

Product Name	3-Chloro-4-Propoxyphenylboronic Acid Pinacol Ester
CAS No.	1688655-72-2
Molecular Formula	C15H22BClO3
Molecular Weight	296.60 g/mol
Synonyms	3-Chloro-4-propoxybenzeneboronic acid pinacol ester; 2-(3-Chloro-4-propoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3-Chloro-4-propoxyphenyl)boronic acid pinacol ester; 3-Chloro-4-propoxybenzeneboronic acid, pinacol ester; Boronic acid, B-(3-chloro-4-propoxyphenyl)-, 1,1-dimethylethyl ester; 3-Chloro-4-propoxy phenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Propoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization including NMR (1H, 13C, 11B), HPLC for purity assessment, and GC for residual solvent analysis to ensure consistency and reliability for sensitive coupling reactions. Certificates of Analysis (COA) with full spectral data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.