Description

1-(2-Iodo-5-Nitro-Phenyl)-Ethanone is a high-purity, specialized aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, featuring both iodo and nitro functional groups on the phenyl ring, which makes it a versatile precursor for constructing complex heterocycles and pharmaceutical intermediates. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active compounds or functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting specific receptors where halogen and nitro groups are critical for activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its reactive sites for structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution reactions due to the presence of the iodine atom.
• Material Science Precursor: Acts as a starting material for synthesizing organic ligands, dyes, or photoactive compounds for advanced material applications.
• Chemical Research & Development: Utilized in academic and industrial labs for methodological development and exploring new chemical transformations.

Basic Information

Product Name	1-(2-Iodo-5-Nitro-Phenyl)-Ethanone
CAS No.	1685280-87-8
Molecular Formula	C8H6INO3
Molecular Weight	291.05 g/mol
Synonyms	2'-Iodo-5'-nitroacetophenone; 1-(2-Iodo-5-nitrophenyl)ethan-1-one; 2-Iodo-5-nitroacetophenone; Ethanone, 1-(2-iodo-5-nitrophenyl)-; 5-Nitro-2-iodoacetophenone; Acetophenone, 2'-iodo-5'-nitro-; α-(2-Iodo-5-nitrophenyl) methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(2-Iodo-5-Nitro-Phenyl)-Ethanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with your specifications. Our commitment to reliable supply and traceable documentation supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.