Description

2-(7-Fluoro-2H-1,3-benzodioxol-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective carbon-carbon bond formation, which is essential for constructing complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed coupling with aryl/vinyl halides to create biaryl structures, a common motif in drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly those containing benzodioxole and fluorinated aromatic systems.
• Agrochemical Research: Serves as a building block for synthesizing new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology & Probe Development: Useful for creating tagged molecules or bioconjugates for studying biological processes and target identification.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries to identify new lead structures in drug discovery campaigns.

Basic Information

Product Name	2-(7-Fluoro-2H-1,3-benzodioxol-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.	1684427-19-7
Molecular Formula	C15H20BFO4
Molecular Weight	294.13 g/mol
Synonyms	7-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-1,3-benzodioxole; 7-Fluoro-1,3-benzodioxol-4-ylboronic acid pinacol ester; 7-Fluoro-4-(pinacolatoboryl)-2H-1,3-benzodioxole; 7-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzodioxole; (7-Fluoro-2H-1,3-benzodioxol-4-yl)boronic acid pinacol ester; 1684427-19-7; 4-Pinacolatoboryl-7-fluoro-1,3-benzodioxole
EINECS	Contact for details

Quality Control

Our 2-(7-Fluoro-2H-1,3-benzodioxol-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient moisture. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.