Description

2-Ethylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex organic molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this boronic ester, fundamental in constructing biaryl structures found in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly in creating complex, functionalized aromatic and heteroaromatic scaffolds.
• Agrochemical Product Development: Employed in the synthesis of advanced herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Research: Acts as a monomer or building block in the creation of organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Useful for bioconjugation and labeling strategies due to the selective reactivity of the protected boronic acid group.
• Scale-up Process Chemistry: The pinacol ester group offers enhanced stability compared to the free boronic acid, making it suitable for multi-step synthesis and larger-scale manufacturing processes.

Basic Information

Product Name	2-Ethylphenylboronic Acid Pinacol Ester
CAS No.	1683582-61-7
Molecular Formula	C14H21BO2
Molecular Weight	232.13 g/mol
Synonyms	2-Ethylbenzeneboronic Acid Pinacol Ester; (2-Ethylphenyl)boronic Acid Pinacol Ester; 2-Ethylphenylboronic Acid Neopentyl Glycol Ester (common alternative); B-(2-Ethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Ethylphenylboronate Pinacol Ester; 2-Ethyl-Benzoic Acid, Boron Derivative, Pinacol Ester; 2-Ethylphenyl-Boron Pinacol Ester
EINECS	Contact for details

Quality Control

Our 2-Ethylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment ensures material consistency for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.