Description

4-Bromo-2-Ethylphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures in modern organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to introduce functionalized aromatic fragments into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex aryl-aryl linkages.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific bromo-ethylphenyl motifs.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis or as a model substrate for catalyst screening.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses serving the life sciences and specialty chemicals sectors.

Basic Information

Product Name	4-Bromo-2-Ethylphenylboronic Acid Pinacol Ester
CAS No.	1674364-30-7
Molecular Formula	C₁₄H₂₀BBrO₂
Molecular Weight	311.02 g/mol
Synonyms	2-(4-Bromo-2-ethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Bromo-2-ethylbenzeneboronic acid pinacol ester; (4-Bromo-2-ethylphenyl)boronic acid pinacol ester; Pinacol 4-bromo-2-ethylphenylboronate; B-(4-Bromo-2-ethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Ethylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full characterization data are provided with every shipment. We support cGMP-compliant production for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.