Description

Ethyl1-Ethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound is critical for enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester coupling partner for the formation of carbon-carbon bonds between aromatic and heteroaromatic systems under mild conditions.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides that require complex heterocyclic architectures.
• Material Science: A precursor for the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Process Chemistry & Scale-Up: Supplied in development and commercial quantities to support the transition from laboratory discovery to industrial-scale manufacturing.

Basic Information

Item	Details
Product Name	Ethyl1-Ethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-2-Carboxylate
CAS No.	1669415-62-6
Molecular Formula	C15H24BNO4
Molecular Weight	293.17 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-ethyl-1H-pyrrole-2-carboxylic acid ethyl ester; Ethyl 1-ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-2-carboxylate; 1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-2-carboxylic Acid Ethyl Ester; 1669415-62-6; Boric acid, cyclic ester with 1-ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl1-Ethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including NMR and HPLC. We support cGMP compliance for pharmaceutical applications and can provide regulatory support documentation upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry, inert atmosphere to prevent moisture absorption and decomposition of the boronic ester moiety.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.