Description

Ethanone, 1-(3-Bromo-5-Chlorophenyl)-2,2,2-Trifluoro- is a high-purity trifluoromethyl ketone derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile halogenated aromatic scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced bioactivity and stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its unique halogenated and fluorinated structure.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) to create more complex biaryl and conjugated systems.
• Fluorine Chemistry Studies: A valuable compound for investigating the effects of fluorine substitution on molecular properties and reactivity in academic and industrial R&D settings.

Basic Information

Product Name	Ethanone, 1-(3-Bromo-5-Chlorophenyl)-2,2,2-Trifluoro-
CAS No.	1655515-91-5
Molecular Formula	C9H5BrClF3O
Molecular Weight	301.49 g/mol
Synonyms	1-(3-Bromo-5-chlorophenyl)-2,2,2-trifluoroethanone; 3'-Bromo-5'-chloro-2,2,2-trifluoroacetophenone; 2,2,2-Trifluoro-1-(3-bromo-5-chlorophenyl)ethanone; 3-Bromo-5-chloro-α,α,α-trifluoroacetophenone; (3-Bromo-5-chlorophenyl)trifluoromethyl ketone; TFAP-BrCl derivative; Bromo-chloro trifluoroacetophenone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(3-Bromo-5-Chlorophenyl)-2,2,2-Trifluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.