Description

(2-Methyl-1-Oxo-1,2-Dihydroisoquinolin-5-Yl)Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and building block essential for modern synthetic chemistry. This compound is a key reagent in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical boron-containing reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules.
• Pharmaceutical Intermediate: Serves as a key building block in the research and production of potential drug candidates, particularly those containing the isoquinolinone scaffold.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where precise molecular design is crucial.
• Chemical Biology & Probe Development: Utilized for synthesizing molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis services catering to specialized R&D projects.

Basic Information

Product Name	(2-Methyl-1-Oxo-1,2-Dihydroisoquinolin-5-Yl)Boronic Acid Pinacol Ester
CAS No.	1655495-97-8
Molecular Formula	C₁₆H₂₀BNO₃
Molecular Weight	285.15 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylisoquinolin-1(2H)-one; 2-Methyl-1-oxo-1,2-dihydroisoquinoline-5-boronic acid pinacol ester; 2-Methyl-1-oxo-1,2-dihydro-5-isoquinolineboronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methyl-1,2-dihydroisoquinolin-1-one; (2-Methyl-1-oxo-1,2-dihydroisoquinolin-5-yl)boronic acid pinacol ester; Boronic acid, B-(2-methyl-1-oxo-1,2-dihydro-5-isoquinolinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of (2-Methyl-1-Oxo-1,2-Dihydroisoquinolin-5-Yl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.