Description

(2-Chloro-4-(6-Methylpyrazin-2-Yl)Phenyl)Boronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its primary commercial value lies in its role as a versatile building block for the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for forming carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly in the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drug candidates containing pyrazine and biphenyl motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific chlorinated aryl structures.
• Material Science Research: Serves as a monomer or building block for creating advanced organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A requested compound for bespoke synthesis projects in fine chemical and custom manufacturing organizations (CMOs).

Basic Information

Product Name	(2-Chloro-4-(6-Methylpyrazin-2-Yl)Phenyl)Boronic Acid
CAS No.	1648864-28-1
Molecular Formula	C11H10BClN2O2
Molecular Weight	248.47 g/mol
Synonyms	(2-Chloro-4-(6-methylpyrazin-2-yl)phenyl)boronic acid; 2-Chloro-4-(6-methylpyrazin-2-yl)benzeneboronic acid; [2-Chloro-4-(6-methylpyrazin-2-yl)phenyl]boronic acid; Boronic acid, B-[2-chloro-4-(6-methyl-2-pyrazinyl)phenyl]-; 2-(4-Borono-3-chlorophenyl)-6-methylpyrazine; 1648864-28-1; B-[2-Chloro-4-(6-methyl-2-pyrazinyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our (2-Chloro-4-(6-Methylpyrazin-2-Yl)Phenyl)Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, purity by HPLC, and identification. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.