Description

Benzeneacetic Acid, 2-[[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methoxy]-, Methyl Ester is a high-value, synthetically versatile boronic ester derivative designed for advanced organic synthesis. This compound matters as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the boronate functional group for selective bond formation.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and bioconjugation reagents for studying biological processes.
• Ligand & Catalyst Development: Acts as a starting material for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis.
• Academic & Contract Research: Essential reagent for methodology development and complex molecule synthesis in university and CRO laboratories.

Basic Information

Product Name	Benzeneacetic Acid, 2-[[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methoxy]-, Methyl Ester
CAS No.	1646563-27-0
Molecular Formula	C24H31BO5
Molecular Weight	410.31 g/mol
Synonyms	Methyl 2-((3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)methyl)phenylacetate; 2-[[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]methyl]benzeneacetic acid methyl ester; (2-Methoxy-2-oxo-1-phenylethyl)methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl ether; Boronic acid, B-[3-[[(2-methoxy-1-methyl-2-oxo-1-phenylethyl)oxy]methyl]phenyl]-, 1,3-propanediol cyclic ester; CAS 1646563-27-0.
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, 2-[[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methoxy]-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.