Description

Benzeneacetic Acid, 4-(2-Bromoacetyl)-α,α-Dimethyl-, Ethyl Ester CAS NO 1645268-51-4 is a specialized brominated aromatic ester building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a bromoacetyl and a dimethyl-substituted acetic acid ethyl ester moiety, makes it a versatile precursor for constructing complex molecular frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating complex ester and ketone functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its bromine atom serves as a reactive handle for further functionalization.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing heterocyclic compounds, complex esters, and other specialty chemicals.
• Material Science Research: Potential precursor in the development of specialty polymers or organic electronic materials due to its aromatic and reactive bromine components.
• Chemical Biology Probes: Can be utilized to synthesize molecular probes for studying enzyme activity or biological pathways.

Basic Information

Product Name	Benzeneacetic Acid, 4-(2-Bromoacetyl)-α,α-Dimethyl-, Ethyl Ester
CAS No.	1645268-51-4
Molecular Formula	C14H17BrO4
Molecular Weight	329.19 g/mol
Synonyms	Ethyl 4-(2-bromoacetyl)-α,α-dimethylbenzeneacetate; 4-(2-Bromoacetyl)-α,α-dimethylbenzeneacetic Acid Ethyl Ester; Benzeneacetic acid, 4-(2-bromoacetyl)-α,α-dimethyl-, ethyl ester; 2-Bromo-1-[4-(1-ethoxycarbonyl-1-methylethyl)phenyl]ethanone; 1-[4-(1-Ethoxycarbonyl-1-methylethyl)phenyl]-2-bromoethanone
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, 4-(2-Bromoacetyl)-α,α-Dimethyl-, Ethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development and cGMP-grade production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.