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Methanone, Bis[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- CAS NO 1643382-78-8


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CAS No.:1643382-78-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methanone, Bis[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a high-purity, advanced organic building block featuring two pinacol boronate ester groups. This compound is a critical intermediate in modern synthetic chemistry, enabling the formation of complex carbon-carbon bonds via cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality precursors for developing new active ingredients and functional polymers.

Application

  • Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in creating biaryl and heterobiaryl structures common in active pharmaceutical ingredients (APIs).
  • Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, herbicides, and fungicides that require specific, complex aromatic frameworks.
  • Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for synthesizing electron-transport materials and host molecules in the fabrication of high-performance OLED displays and lighting.
  • Polymer & Materials Science: Employed in the development of conjugated polymers, organic semiconductors, and metal-organic frameworks (MOFs) for electronic and sensing applications.
  • Ligand & Catalyst Development: Utilized to create sophisticated bidentate or multidentate ligands for transition metal catalysts used in asymmetric synthesis and other catalytic processes.
  • Chemical Research & Development: An essential reagent for academic and industrial R&D labs exploring new synthetic methodologies and constructing complex molecular architectures.

Basic Information

Item Detail
Product Name Methanone, Bis[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No. 1643382-78-8
Molecular Formula C27H36B2O5
Molecular Weight 486.19 g/mol
Synonyms 4,4'-(Carbonylbis(4,1-phenylene))bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane); Bis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone; 4,4'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzophenone; Benzophenone-4,4'-diylbis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane); 4,4'-Diboronobenzophenone pinacol ester; (4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone
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Quality Control

Our Methanone, Bis[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR (1H and 13C), and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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