Description

2-(5-Methoxy-2-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 1641570-76-4 is a high-purity boronic ester derivative, serving as a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient and selective cross-coupling reactions, which are fundamental to constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-boron functionalities.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for diagnostic and research applications.
• Custom Synthesis: A versatile reagent for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.

Basic Information

Item	Details
Product Name	2-(5-Methoxy-2-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1641570-76-4
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	5-Methoxy-2-methylbenzeneboronic acid pinacol ester; (5-Methoxy-2-methylphenyl)boronic acid pinacol ester; 2-Methyl-5-methoxyphenylboronic acid pinacol ester; 2-(5-Methoxy-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Methoxy-o-tolylboronic acid pinacol ester; 1641570-76-4; BRN 9086665
EINECS	Contact for details

Quality Control

Every batch of 2-(5-Methoxy-2-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. We guarantee high chemical purity and lot-to-lot consistency through comprehensive analytical testing, including NMR, HPLC, and GC analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.