Description

4-(1,3,2-Dioxaborinan-2-Yl)Phenol is a versatile boronic ester derivative of phenol, serving as a critical synthetic intermediate in modern organic chemistry. Its primary value lies in its role as a protected phenolic boronic acid, offering enhanced stability and solubility for cross-coupling reactions compared to its free acid form. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require phenolic-boronate motifs.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating complex organic molecules used in electronic displays and optoelectronic devices.
• Polymer & Resin Modification: Incorporated into polymer backbones to introduce phenol and boronate functionalities, altering material properties.
• Chemical Biology & Proteomics: Utilized as a probe or linker in bioconjugation chemistry and the development of enzyme inhibitors.
• Organic Synthesis Research: A valuable reagent for academic and industrial R&D laboratories exploring new C-C bond formation methodologies.

Basic Information

Product Name	4-(1,3,2-Dioxaborinan-2-Yl)Phenol
CAS No.	1640035-73-9
Molecular Formula	C9H11BO3
Molecular Weight	177.99 g/mol
Synonyms	4-(1,3,2-Dioxaborinan-2-yl)phenol; 4-(2-Phenoxy-1,3,2-dioxaborinan-2-yl)phenol; Phenol, 4-(1,3,2-dioxaborinan-2-yl)-; 4-Hydroxyphenyl-1,3,2-dioxaborinane; 2-(4-Hydroxyphenyl)-1,3,2-dioxaborinane; B-(4-Hydroxyphenyl)-1,3,2-dioxaborinane; Protected 4-Hydroxyphenylboronic Acid
EINECS	Contact for details

Quality Control

Our 4-(1,3,2-Dioxaborinan-2-Yl)Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with lot-specific data are provided to guarantee consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.