Description

(2-Fluoro-3-(Methoxycarbonyl)Phenyl)Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a critical step in constructing complex molecules for active pharmaceutical ingredients (APIs). This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce functionalized biaryl structures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Enables the formation of carbon-carbon bonds to create complex biaryl and heterobiaryl structures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a precursor for organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology: Utilized in the synthesis of probes and ligands for target identification and validation.
• Custom Synthesis: A critical reagent for contract research and manufacturing organizations (CROs/CMOs) performing bespoke chemical synthesis.

Basic Information

Product Name	(2-Fluoro-3-(Methoxycarbonyl)Phenyl)Boronic Acid Pinacol Ester
CAS No.	1638847-77-4
Molecular Formula	C₁₄H₁₈BFO₄
Molecular Weight	280.10 g/mol
Synonyms	(2-Fluoro-3-(methoxycarbonyl)phenyl)boronic acid pinacol ester; 2-Fluoro-3-(methoxycarbonyl)benzeneboronic acid pinacol ester; (3-Carbomethoxy-2-fluorophenyl)boronic acid pinacol ester; Methyl 2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 2-Fluoro-3-methoxycarbonylbenzeneboronic acid pinacol ester; B-(2-Fluoro-3-methoxycarbonylphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our (2-Fluoro-3-(Methoxycarbonyl)Phenyl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.