Description

1-Bromo-2-Chloro-5-Iodo-4-Methoxy-Benzene is a highly functionalized, multi-halogenated benzene derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides requiring specific halogenated aromatic cores.
• Material Science: Serves as a monomer or precursor for functional polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to its bromo and iodo substituents.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and heterocyclic chemistry.
• Dye & Pigment Industry: Potential intermediate for synthesizing specialized halogenated dyes and pigments.

Basic Information

Product Name	1-Bromo-2-Chloro-5-Iodo-4-Methoxy-Benzene
CAS No.	1629269-81-3
Molecular Formula	C7H5BrClIO
Molecular Weight	347.38 g/mol
Synonyms	2-Bromo-1-Chloro-4-Iodo-5-Methoxybenzene; 4-Methoxy-2-Bromo-1-Chloro-5-Iodobenzene; 1-Bromo-2-chloro-5-iodo-4-methoxybenzene; Benzene, 1-bromo-2-chloro-5-iodo-4-methoxy-; 1629269-81-3
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-5-Iodo-4-Methoxy-Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.