Description

n-Ethyl-6-Methyl-7-Oxo-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[2,3-C]Pyridine-2-Carboxamide is a sophisticated heterocyclic compound featuring a pyrrolopyridine core integrated with a pinacol boronate ester functional group. This structure makes it a highly valuable building block for modern synthetic chemistry, particularly in cross-coupling reactions. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients. The compound's unique scaffold facilitates the exploration of new chemical space in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: The pinacol boronate ester group serves as a versatile handle for forming carbon-carbon bonds with aryl/heteroaryl halides, a cornerstone of medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by providing a complex heterocyclic template.
• Material Science Exploration: Acts as a monomer or functional unit in the research of advanced organic electronic materials and polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Contract Research & Development (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and process chemistry projects.

Basic Information

Item	Details
Product Name	n-Ethyl-6-Methyl-7-Oxo-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[2,3-C]Pyridine-2-Carboxamide
CAS No.	1628864-80-1
Molecular Formula	C20H26BN3O4
Molecular Weight	383.25 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-ethyl-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide; 1H-Pyrrolo[2,3-c]pyridine-2-carboxamide, N-ethyl-6-methyl-7-oxo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Boronic acid, B-[2-[(ethylamino)carbonyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl]-, pinacol ester; CAS 1628864-80-1; 4-BPin-substituted pyrrolopyridine carboxamide; Pinacol ester of 4-borono-N-ethyl-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide
EINECS	Contact for details

Quality Control

Our production of n-Ethyl-6-Methyl-7-Oxo-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[2,3-C]Pyridine-2-Carboxamide adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR (1H, 13C, 11B), and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.